Composition for cryoprotection including DNA nanostructure, and method for using same

A composition for cryopreservation comprising:

• a nucleic acid structure which comprises a scaffold nucleic acid folded at predetermined positions to form multiple strands, a plurality of first staple nucleic acids wherein at least a portion of a sequence thereof comprises a complementary sequence to that of the scaffold nucleic acid, which are bound to at least one of the strands of the scaffold nucleic acid to form a double strand, and a plurality of second staple nucleic acids wherein at least a portion of a sequence thereof is complementary to that of the scaffold nucleic acid but at least one end thereof is not complementary thereto, which are bound to at least one of the strands of the scaffold nucleic acid to form a double strand and a single strand at the end thereof;
• linkers coupled to at least one of single strands in the nucleic acid structure;
• and
• an anti-freezing peptide coupled to at least one of the linkers.