Precision-based immuno-molecular augmentation (PBIMA) computerized system, method, and therapeutic vaccine

A precision-based immunomolecular augmentation (PBIMA) apparatus for designing and treating a patient with customized therapeutic peptides or peptide vaccine, comprising:

• at least a processor;
• and
• a memory communicatively connected to the at least a processor, the memory containing instructions configuring the at least a processor to:
• receive a data input comprising patient data comprising one or more of patient transcriptomics data and patient urine proteomics data;
• compute a precision data output of a vaccine composition specific to a patient's profile and configured to elicit an effective therapeutic response against a patient disease, the computing comprising,
• identifying a plurality of therapeutic peptide sequences, and ranking the plurality of therapeutic peptide sequences as a function of biomarker expression levels of an organoid to use in the vaccine composition;
• and
• conduct an immunopeptide synthesis and manufacturing of the vaccine composition;
• wherein the patient has been diagnosed with and/or is genetically predisposed to one or more diseases comprising a cancer, an autoimmune disease, a neurodegenerative disease, and/or a pathogenic infectious disease.