Methods and systems for improved quality assurance for high-throughput analysis

A system for confirming identification of samples processed by a high-throughput analytical technique comprising:

• a station or component configured to distribute a plurality of individual samples to individual predetermined positions of a multi-sample test unit;
• a station or component configured to distribute an identifier material to at least one predetermined position of the multi-sample test unit;
• a station or component configured to measure, by mass spectrometry, an absence or presence of an analyte in the plurality of individual samples;
• and,
• a station or component configured to measure, by mass spectrometry, the identifier material, wherein the measured identifier material at the predetermined position of the multi-sample test unit is used to confirm the identity of the plurality of individual samples positioned in the multi-sample test unit, and wherein the identifier material is selected from a compound that is distinct from the analyte and distinct from an internal standard used to assess quantitative recovery of the analyte, but that wherein the compound can be detected using a same analysis as the analyte.