Process for storing and releasing protein-decorated nanoparticles on paper substrates
AssigneesUniversitat De Les Illes Balears, Fundació Institut D'Investigació SanitàRia Illes Balears
InventorsRoberto De La Rica Quesada, Francy Alejandra Alba Patiño, Cristina Adrover Jaume
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Abstract
The invention relates to a process for storing protein-decorated nanoparticles on paper substrates without irreversible binding, and particularly for storing protein-decorated nanoparticles within paper substrates modified with a polymer. The invention also relates to a reservoir containing protein-decorated nanoparticle capable of stablishing biological interactions obtained by the process and its use in biosensors made of paper.
Claims23
A process for obtaining a reservoir comprising protein-decorated nanoparticles on paper substrates, the process comprising:
- (i) treating a paper substrate with a hydrophilic negatively charged polymer over the paper substrate, wherein the polymer is polystyrene sulfonate (PSS);
- and
- (ii) applying protein-decorated nanoparticles over the paper substrate obtained in step (i);
- and
- (iii) releasing the nanoparticles from the reservoir.
Dependencies are inferred from the claim text.