VSV chimeric vectors
AssigneesVira Therapeutics GmbH, Boehringer Ingelheim International GmbH
InventorsTobias Nolden, Patrik Erlmann, Guido Wollmann, Zoltan Banki, Bart Spiesschaert, Janine Kimpel, Dorothee Von Laer
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Abstract
The present invention relates to VSV chimeric vectors, characterized in that the vectors comprise a gene coding for a glycoprotein GP of the Dandenong virus (DANDV) or Mopeia vims (MOPV) and lack a functional gene coding for envelope protein G of the VSV. The invention also provides VSV chimeric vector systems. In addition, the invention relates to uses of the VSV chimeric vectors and systems of the invention, including the use in medicine such as in the treatment of solid tumors.
Claims3
VSV chimeric vector, comprising a gene coding for a glycoprotein GP of the Dandenong virus and lacking a functional gene coding for envelope protein G of the VSV.
Dependencies are inferred from the claim text.