Amphiphilic copolymer with zwitterionic and fluorinated moieties
AssigneeCornell University
InventorsRong Yang, Trevor Franklin
Life of this patent
Estimating the term…
Abstract
Provided are amphiphilic copolymers that include repeat units of formulas [Z]m and [P]n, wherein Z is a zwitterionic structural unit including at least one pendant heteroaromatic moiety, the heteroaromatic moiety containing a positively charged quaternary nitrogen atom (e.g., a pyridine ring), and wherein at least one negatively charged functional moiety is linked to the heteroaromatic moiety directly or through a linker, wherein the linker, where present, is an optionally substituted alkyl linker; P is a structural unit including a hydrophobic moiety, the hydrophobic moiety being a linear, branched, or cyclic fluorine-substituted C1-C20 moiety; m is an integer that is ≥1; and n is an integer that is ≥1.
Claims22
An amphiphilic copolymer comprising two or more structures of formula (i)-(vi):
- wherein
- Z is a hydrophilic zwitterionic structural unit comprising at least one pendant heteroaromatic moiety, wherein the heteroaromatic moiety comprises a positively charged quaternary nitrogen atom, and wherein at least one negatively charged functional moiety is linked to the heteroaromatic moiety directly or through a linker, wherein the linker, where present, is an optionally substituted alkylene linker;
- P is a hydrophobic structural unit comprising a hydrophobic moiety, said hydrophobic moiety being or comprising a linear, branched, or cyclic fluorine-substituted C1-C20 alkyl moiety;
- X is a crosslinking moiety;
- m is an integer that is ≥1;
- n is an integer that is ≥1;
- o is an integer selected from 1 to 10,000;
- wherein the amphiphilic copolymer has hydrophilic zwitterionic structural units and hydrophobic structural units randomly distributed therein, and wherein the comonomer residues are located randomly in the copolymer molecule and are configured to have reversible surface chain reorientation in response to surface wetting and/or drying to switch between a first surface energy state and a second surface energy state;
- wherein the amphiphilic copolymer comprises a plurality of domains having hydrophilic units and hydrophobic units, and wherein each of the domains has a size smaller than 2 nm2;
- and
- wherein the crosslinking moiety X is selected from a unit of polymerized monomer selected from arylene, alkylene, phenylene, 1,4-phenylene, divinylbenzene, ethylene glycol dimethacrylate, ethylene glycol diacrylate, vinyl methacrylate, allyl methacrylate, maleic anhydride, 1,3,5-trivinyltrimethylcyclotrisiloxane glycidyl methacrylate, and di(ethylene glycol)divinyl ether, or any combination thereof.
Dependencies are inferred from the claim text.