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US 12,522,656 B2Granted
Anti-G-protein alpha antibody
AssigneeCisbio Bioassays
InventorsElodie Dupuis, Thomas Roux, Eric Trinquet
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Abstract
The invention relates to antibodies or antibody fragments capable of binding to G-protein alpha, nucleic acid sequences coding for the antibody, vectors comprising the nucleic acid sequence, cells comprising the vector or the nucleic acid sequence and a kit-of-parts comprising (i) the antibody or antibody fragment or the composition and (ii) a source of GTP labeled with a member of a pair of RET partners.
Claims18
An antibody or antibody fragment capable of binding to G-protein alpha, which comprises:
- a heavy chain variable domain comprising a CDR1 of amino acid sequence SEQ ID NO:
- 1, a CDR2 of amino acid sequence SEQ ID NO:
- 2, and a CDR3 of amino acid sequence SEQ ID NO:
- 3;
- and
- a light chain variable domain comprising a CDR1 of amino acid sequence SEQ ID NO:
- 4, a CDR2 of amino acid sequence DTS, and a CDR3 of the light chain variable domain consists of the amino acid sequence SEQ ID NO:
- 5.
5 more elements
Dependencies are inferred from the claim text.