Cyclophilin inhibitors and uses thereof
AssigneeFarsight Medical Technology (Shanghai) Co., Ltd.
InventorsChing-Pong Mak, Hans Fliri, Fashu Ma, Michael Peel
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Abstract
Compounds defined by Formula 4 are used as cyclophilin inhibitors for the prevention or treatment of diseases or disorders, in particular diseases or conditions associated with cellular injury or cell death, such as organ injury or organ failure, which can be caused by a number of different reasons, such as ischemia or ischemia reperfusion injury, toxins, infection or mechanical trauma.
Claims15
A pharmaceutical composition comprising a therapeutically effective amount of a compound or a pharmaceutically acceptable salt thereof selected from the group consisting of
- and one or more pharmaceutically acceptable excipients.
A method of treatment of a cyclophilin-mediated disease or condition, the method comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a therapeutically effective amount of a compound or a pharmaceutically acceptable salt thereof selected from the group consisting of
- and one or more pharmaceutically acceptable excipients.
Dependencies are inferred from the claim text.