Methods for real-time image guided radiation therapy
AssigneeRefleXion Medical, Inc.
InventorsYevgen Voronenko, Peter Demetri Olcott, Debashish Pal, Rostem Bassalow
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Abstract
Disclosed herein are systems and methods for guiding the delivery of therapeutic radiation using incomplete or partial images acquired during a treatment session. A partial image does not have enough information to determine the location of a target region due to, for example, poor or low contrast and/or low SNR. The radiation fluence calculation methods described herein do not require knowledge or calculation of the target location, and yet may help to provide real-time image guided radiation therapy using arbitrarily low SNR images.
Claims50
A radiation therapy system comprising:
- a therapeutic radiation source that is rotatable about a patient area;
- a multi-leaf collimator (MLC) located in a beam path of the therapeutic radiation source;
- an imaging system for acquiring imaging data of the patient area;
- and
- a controller configured to generate radiation delivery instructions from a radiation fluence map, wherein the radiation delivery instructions comprise MLC instructions and therapeutic radiation source instructions.
A radiation therapy system comprising:
- a continuously rotatable gantry;
- a therapeutic radiation source mounted on the gantry and movable to a plurality of firing positions by the gantry;
- a multi-leaf collimator (MLC) mounted on the gantry and located in a beam path of the radiation therapy source;
- one or more imaging sensors mounted on the gantry;
- and
- a controller in communication with the gantry, the radiation source, the multi-leaf collimator and the one or more imaging sensors, and configured to generate radiation delivery instructions, wherein generating radiation delivery instructions comprises:
- calculating a fluence map fcalc using imaging data from the one or more imaging sensors and a cumulative residual fluence map Δfcumulative;
- and
- segmenting the fluence map fcalc into a set of radiation delivery instructions comprising MLC instructions and therapeutic radiation source instructions for each firing position over one or more gantry rotations.
A method for real-time fluence map segmentation for radiation delivery, the method comprising:
- acquiring imaging data from one or more imaging sensors mounted on a continuously rotatable gantry during a session;
- calculating a fluence map fcalc using the imaging data and a cumulative residual fluence map Δfcumulative;
- and
- segmenting the fluence map fcalc during the session into a set of radiation delivery instructions for one or more radiation firing positions over one or more gantry rotations.
Dependencies are inferred from the claim text.