Non-invasive agent applicator
AssigneeMuPharma Pty Ltd
InventorsHarry Unger, Mark Unger, Sean Michael Langelier
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Abstract
There is disclosed systems and methods for non-invasive delivery of an agent to biological tissues. Delivery of the agent to the tissues can be by one or more modalities. In some embodiments the systems and methods use agent carrier body including a tissue contacting surface for non-invasively engaging tissues under treatment. The tissue contacting surface can be at least partly defined by a plurality of protrusions that are in fluid communication with one or more reservoirs forming part of the agent carrier body. The protrusions may extend outward from an inside of a void and terminate at said tissue contacting surface.
Claims20
A method of inducing a mucosal immune response in a mucosal tissue of a subject, the method comprising:
- providing a solid agent carrier body comprising a plurality of channels integral with and extending at least partially through the agent carrier body and terminating at a tissue contacting surface of the agent carrier body in a series of individual pores of up to 1000 μm in size;
- holding an agent within the channels in the agent carrier body;
- non-invasively applying the tissue contacting surface of the agent carrier body directly to a surface of mucosal epithelial tissue of an inner lip of the subject;
- and
- non-invasively delivering the agent held in the channels of the agent carrier body to the mucosal epithelial tissue by applying ultrasonic waves longitudinally along the channels, wherein the mucosal epithelial tissue remains intact during delivery, and wherein delivery of the agent induces at least the mucosal immune response in the subject.
Dependencies are inferred from the claim text.