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US 12,521,424 B2Granted
Optimized oncolytic viruses and uses thereof
AssigneeSator Therapeutics
InventorsPeter M. Chumakov, Anastasia V. Lipatova, Stepan P. Chumakov, Natalia D. Tararova, Stephen A. Charles, Anton A. Komar
Life of this patent
Estimating the term…
Abstract
Methods of inhibiting or reducing tumor growth are disclosed. A composition containing at least one selected oncolytic virus is administered within a tumor of a patient. The virus kills cancerous cells and induces a systemic and lasting anti-tumor immunity that is also compatible with other cancer treatments. Also disclosed are methods of creating synthetic viruses for targeting cancerous tumors.
Claims9
A method of treating a tumor in a dog or cat, comprising:
- administering to the dog or cat a first composition containing an effective amount of at least a first oncolytic virus for a first time period, wherein the first oncolytic virus is Sendai virus;
- and
- after the first time period, administering to the dog or cat a second composition containing an effective amount of at least a second oncolytic virus for a second time period, wherein the second oncolytic virus is Reovirus Type 1.
Dependencies are inferred from the claim text.