Non-aqueous gel composition
AssigneeAmaterasu Lifesciences LLP
InventorMaharukh Rustomjee
Life of this patent
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Abstract
A non-aqueous gel composition comprising silicone crosspolymer, silicone oil and a sweat and/or sebum absorbing agent wherein the composition is used to prevent or treat symptoms associated with a topical skin disorder in a human patient. The present invention also relates to method of preventing or treating a topical skin disorder using a non-aqueous gel composition.
Claims18
A method of treating a topical disorder in a human in need thereof comprising administering to the human in need thereof a non-aqueous gel comprising:
- (a) one or more silicone crosspolymers selected from the group consisting of dimethicone/vinyldimethicone crosspolymers, dimethicone crosspolymers, phenylvinyldimethicone crosspolymers, dimethicone/phenylvinyl dimethicone crosspolymers, vinyl dimethicone/methicone silsesquioxane crosspolymers, dimethicone/polyethylene glycol (PEG-10/15) crosspolymers, polyethylene glycol (PEG-15)/Lauryldimethicone crosspolymers and mixtures thereof being present at 1% w/w-30% w/w of the non-aqueous gel;
- (b) a silicone oil being present at about 50% w/w to about 99% w/w of the non-aqueous gel;
- and
- (c) a sweat or sebum absorbing agent selected from the group consisting of silica silylate, magnesium alumina meta silicate, engineered particles of silica, polysilicic acids, silicic anhydride, fumed silica, hydrated silica, silica gel, silicate esters, silicate salts, starch, and combinations thereof being present at 0.1% w/w-25% w/w of the non-aqueous gel.
A method of treating a diaper rash in a human in need thereof comprising contacting the skin surface of a human in need thereof with a non-aqueous gel composition comprising:
- (a) one or more silicone crosspolymers selected from the group consisting of dimethicone/vinyldimethicone crosspolymers, dimethicone crosspolymers, phenylvinyldimethicone crosspolymers, dimethicone/phenylvinyl dimethicone crosspolymers, vinyl dimethicone/methicone silsesquioxane crosspolymers, dimethicone/polyethylene glycol (PEG-10/15) crosspolymers, polyethylene glycol (PEG-15)/Lauryldimethicone crosspolymers and mixtures thereof being present at 1% w/w-30% w/w of the non-aqueous gel;
- (b) a silicone oil being present at about 50% w/w to about 99% w/w of the non-aqueous gel;
- (c) a sweat and/or sebum absorbing agent selected from the group consisting of silica silylate, magnesium alumina meta silicate, engineered particles of silica, polysilicic acids, silicic anhydride, fumed silica, hydrated silica, silica gel, silicate esters, silicate salts, starch, and combinations thereof being present at 0.1% w/w-25% w/w of the non-aqueous gel;
- and
- (d) a skin rejuvenating agent or soothing agent is selected from the group consisting of curcumin, balloon vine extract, echium oil, blackcurrant seed oil, sunflower oil concentrate, tea tree oil, tulsi, neem oil, coconut oil, olive oil, geranium oil, lavender oil, cinnamon oil, calendula oil, calamine, tocopherol acetate, squalene, squalane, patchouli oil, lemongrass oil, lemon oil and combinations thereof being present at 0.1% w/w-25% w/w of the non-aqueous gel.
A method of treating bed sores or pressure ulcers in a human in need thereof comprising contacting the skin surface of a subject in need thereof with a non-aqueous gel comprising:
- (a) one or more silicone crosspolymers selected from the group consisting of dimethicone/vinyldimethicone crosspolymers, dimethicone crosspolymers, phenylvinyldimethicone crosspolymers, dimethicone/phenylvinyl dimethicone crosspolymers, vinyl dimethicone/methicone silsesquioxane crosspolymers, dimethicone/polyethylene glycol (PEG-10/15) crosspolymers, polyethylene glycol (PEG-15)/Lauryldimethicone crosspolymers and mixtures thereof being present at 1% w/w-30% w/w of the non-aqueous gel;
- (b) a silicone oil being present at about 50% w/w to about 99% w/w of the non-aqueous gel;
- and
- (c) a sweat and/or sebum absorbing agent selected from the group consisting of silica silylate, magnesium alumina meta silicate, engineered particles of silica, polysilicic acids, silicic anhydride, fumed silica, hydrated silica, silica gel, silicate esters, silicate salts, starch, and combinations thereof being present at 0.1% w/w-25% w/w of the non-aqueous gel.
Dependencies are inferred from the claim text.