Injectable compositions
AssigneeBoston Scientific Scimed, Inc.
InventorsJoseph T. Delaney, Jr., Samuel Raybin, John Kummailil, Matthew B. Hollyer
Life of this patent
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Abstract
The present disclosure relates to injectable compositions sterile injectable fluid compositions comprising a polysaccharide having a color in the visible spectrum, methods of forming the same, kits containing the same, and methods for performing agent-assisted procedures in a patient using the same.
Claims17
A method comprising injecting a sterile injectable fluid composition at a target site within a subject, the sterile injectable fluid composition comprising water and a hydrophilic polymer having a color in the visible spectrum either as a result of reflection of incident visible light or as a result of absorption of incident radiation having a first wavelength and re-emission of light having a second wavelength, longer than the first wavelength, in the visible spectrum, wherein the hydrophilic polymer comprises a polysaccharide gum, wherein the sterile injectable solution exhibits decreasing viscosity under shear, and wherein the hydrophilic polymer comprises a covalently attached dye molecule.
A method comprising:
- injecting a sterile injectable fluid composition at a target site within a subject, the sterile injectable fluid composition exhibiting decreasing viscosity under shear and the sterile injectable fluid composition comprising water and a hydrophilic polymer having a color in the visible spectrum either as a result of reflection of incident visible light or as a result of absorption of incident radiation having a first wavelength and re-emission of light having a second wavelength, longer than the first wavelength, in the visible spectrum, wherein the hydrophilic polymer comprises a polysaccharide gum, wherein the sterile injectable solution exhibits decreasing viscosity under shear, and wherein the hydrophilic polymer comprises a covalently attached dye molecule;
- and
- performing a surgical procedure at the target site wherein tissue is removed from the target site.
A method of forming a water-soluble polysaccharide gum having a color in the visible spectrum, comprising reacting a water-soluble polysaccharide with a dye molecule comprising one or more of the following reactive groups:
- a monochlorotriazine group, a monofluorochlorotriazine group, a dichlorotriazine group, a difluorochloropyrimidine group, a dichloroquinoxaline group, a trichloropyrimidine group, a vinyl sulfone group, a vinyl amide group, or a sulfonyl fluoride group.
Dependencies are inferred from the claim text.