Back to results
US 12,517,141 B2Granted
Methods of estimating blood glucose and related systems
AssigneeThe General Hospital Corporation
InventorsRoy Malka, John M. Higgins, David M. Nathan
Life of this patent
Estimating the term…
Abstract
A method includes estimating a value of a parameter indicative of an age or lifespan of a population of red blood cells of a subject, estimating a value of average glucose (AG) of the subject based on (i) the value of the parameter and (ii) a value indicative of an amount of glycated hemoglobin (HbA1c) of the subject, and providing information for treatment or diagnosis of a hyperglycemia condition of the subject based on the estimated value of AG.
Claims18
A glucose monitoring device comprising:
- a glucose sensor configured to measure one or more values indicative of blood glucose concentration of a subject when the glucose monitoring device is worn by the subject, the one or more values indicative of blood glucose concentration being further indicative of an estimated value of a parameter indicative of an average age or lifespan of a population of red blood cells of the subject;
- a user terminal configured to provide information to the subject or a healthcare provider;
- and
- a controller configured to execute instructions to perform one or more operations comprising:
- estimating the value of the parameter, wherein estimating the value of the parameter comprises determining a linear relationship between the one or more values indicative of blood glucose concentration and one or more values indicative of an amount of glycated hemoglobin (HbA1c) of the subject, wherein the parameter defines a slope of the linear relationship;
- estimating a value of average glucose (AG) based on (i) the estimated value of the parameter and (ii) a value of the one or more values indicative of an amount of HbA1c of the subject, and
- providing, via the user terminal, an amount of insulin or insulin analog to be administered to the subject to treat a hyperglycemia condition of the subject, the amount of the insulin or insulin analog being a function of the estimated value of AG.
4 more elements
A glucose monitoring device comprising:
- a glucose sensor configured to measure a value indicative of blood glucose concentration of a subject when the glucose monitoring device is worn by the subject, the value indicative of blood glucose concentration being further indicative of an estimated value of a parameter indicative of an average age or lifespan of a population of red blood cells of the subject;
- a user terminal configured to provide information to the subject or a healthcare provider;
- and
- a controller configured to execute instructions to perform one or more operations comprising:
- receiving a value of AG estimated based on (i) the value indicative of blood glucose concentration and (ii) a value indicative of HbA1c, wherein estimating the AG comprises estimating the value of the parameter, comprising determining a linear relationship between one or more values indicative of blood glucose concentration and one or more values indicative of an amount of HbA1c of the subject, wherein the parameter defines a slope of the linear relationship, and
- providing, via the user terminal, an amount of insulin or insulin analog to be administered the subject to treat a hyperglycemia condition of the subject, the amount of the insulin or insulin analog being a function of the estimated value of AG.
3 more elements
A glucose monitoring device comprising:
- a glucose sensor configured to measure a value indicative of blood glucose concentration of a subject when the glucose monitoring device is worn by the subject, the value indicative of blood glucose concentration being further indicative of an estimated value of a parameter indicative of an age or lifespan of a population of red blood cells of the subject;
- a user terminal configured to provide information to the subject or a healthcare provider;
- and
- a controller configured to execute instructions to perform one or more operations comprising:
- determining a subject-specific relationship between values indicative of blood glucose concentration and values indicative of an amount of HbA1c for the subject based on the parameter, wherein the subject-specific relationship is a linear relationship between the values indicative of AG and the values indicative of the amount of HbA1c, wherein the parameter defines a slope of the linear relationship;
- and
- providing, via the user terminal, an amount of insulin or insulin analog to be administered to the subject to treat a hyperglycemia condition of the subject, the amount of insulin or insulin analog being a function of the subject-specific relationship.
4 more elements
Dependencies are inferred from the claim text.