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US 12,516,365 B2Granted
Biocide compositions compatible with enzyme biosensors and methods of use thereof
AssigneeInstrumentation Laboratory Company
InventorsDennis Robert Conlon, Prasad Pamidi
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to biocide compositions compatible with enzyme biosensors and methods for using same. More particularly, the disclosure relates to biocide compositions compatible with enzymes used for measuring creatine and creatinine levels.
Claims20
A system comprising:
- an in vitro critical care analyzer configured to perform multiple different assays and to measure multiple different analytes, the in vitro critical care analyzer comprising:
- a cartridge for the in vitro critical care analyzer, the cartridge being configured for insertion into the in vitro critical care analyzer, the cartridge comprising:
- a sensor comprising:
- an electrode;
- an enzyme layer over the electrode, the enzyme layer comprising one or more enzymes for measurement of one or more of creatine, creatinine, urea, or blood urea nitrogen;
- and
- a diffusion control membrane over the enzyme layer;
- and
- containers holding solutions that are different, that are liquid, and that are to contact the sensor for different purposes, one or more of the solutions comprising one or more biocides, the one or more biocides comprising Levofloxacin or Polymyxin.
6 more elements
A system comprising:
- a cartridge for an in vitro critical care analyzer, the cartridge being configured for insertion into the in vitro critical care analyzer, the cartridge comprising:
- a sensor comprising:
- an electrode;
- and
- an enzyme layer over the electrode, the enzyme layer comprising one or more enzymes for measurement of one or more of creatine, creatinine, urea, or blood urea nitrogen;
- and
- containers holding liquid solutions that are different and that are to contact the sensor for different purposes, one or more of the liquid solutions comprising:
- an enzyme compatible biocide comprising Levofloxacin or Polymyxin.
5 more elements
Dependencies are inferred from the claim text.