Back to results
US 12,516,357 B1Granted
Modified host cells for high efficiency production of vanillin
AssigneeAmyris, Inc.
InventorLauren Raetz
Life of this patent
Estimating the term…
Abstract
Provided herein are genetically modified host cells, compositions, and methods for improved production of vanillin and/or glucovanillin. The host cells, compositions, and methods described herein provide an efficient route for the heterologous production of vanillin and/or glucovanillin and any compound that can be synthesized or biosynthesized from either or both.
Claims39
A genetically modified yeast host cell capable of producing vanillin or glucovanillin comprising:
- (a) one or more nucleic acids comprising nucleic acids capable of overexpressing SHM2, SAH1, MET6, and MET13;
- or SHM2, SAH1, MET6, and a chimeric MET13;
- and
- (b) deletion of ADH6.
1 more element
Dependencies are inferred from the claim text.