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US 12,516,094 B2Granted
Pharmaceutical preparation
AssigneeFerring International Center S.A.
InventorsIan Cottingham, Daniel Plaksin, Richard Boyd White
Life of this patent
Estimating the term…
Abstract
Preparations including recombinant FSH (rFSH).
Claims7
A method of manufacturing recombinant follicle stimulating hormone (FSH) comprising α2,3- and α2,6-sialylation, the method comprising a step of producing or expressing recombinant FSH in a human cell line, wherein the human cell line has been modified using an α2,3-sialyltransferase, wherein the recombinant FSH comprises α2,3- and α2,6-sialylation, and wherein from 5% to 20% of the total sialylation of the recombinant FSH is α2,6-sialylation.
Dependencies are inferred from the claim text.