Crystal form of 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative
AssigneeHyundai Pharm Co., Ltd.
InventorsJeong Un Hwang, Jin Woong Kim, Kyu Hwan Lee, Eun Young Kim, Su Kyoung Choi
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Abstract
The present invention relates to a novel crystal form of a 3-(4-(benzyloxy)phenyl)hex-4-inoic acid derivative, a preparation method therefore and a pharmaceutical composition comprising same. A crystal form I of a compound of chemical formula 1, according to the present invention, exhibits more excellent physicochemical properties such as thermal stability, static electricity-inducing capability, compressibility, etc. compared to an amorphous form or a crystal form II, and thus is especially useful for preparation and long-term storage.
Claims11
A crystal form I of a compound of Chemical Formula 1,
- wherein the crystal form exhibits an X-ray powder diffraction pattern having 4 or more diffraction peaks at 2[θ] values selected from 4.61±0.2, 5.49±0.2, 6.84±0.2, 11.74±0.2, 12.05±0.2, 13.74±0.2, 16.50±0.2, 16.94±0.2, 18.45±0.2, 19.11±0.2, 20.13±0.2, 20.42±0.2, 20.87±0.2, 21.57±0.2, 23.04±0.2, and 25.02±0.2.
Dependencies are inferred from the claim text.