Melt blown dressing with gradient density
AssigneeEthicon, Inc.
InventorsSai Veruva, Jianguo Zhou, Joseph Vliet, Gerard Llanos, Kenneth Keilman
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Abstract
The present invention is directed to an absorbable hemostatic nonwoven patch that utilizes a biocompatible substrate comprised of melt-blown microfibers as webbed sheets that are layered and bonded/entangled in descending density and ascending porosity; with the substrate having a high flexibility, strength and porosity that is suitable for coating cross-linkable active molecules and ability for laparoscopic use or trocar deployment, ultimately for functional use as a highly effective hemostat in addressing problematic bleeding during both open and minimally invasive surgical procedures.
Claims18
A method for preparing a wound dressing comprising a melt-blown multi-layered substrate of a polymeric material having at least two major surfaces and a coated layer that is applied to at least one of the major surfaces of a sealing agent that is selected from the group consisting of co-reactive hydrogel-forming materials, one or more plasma-based hemostatic agents and combinations thereof, wherein the melt-blown substrate has a porosity gradient profile, said method comprising melt blowing microfibers as webbed sheets, layering the melt-blown sheets, and bonding the layers melt-blown sheets.
Dependencies are inferred from the claim text.