Oral composition and methods
AssigneeWenzhou Qingcheng Healthcare Tech Ltd.
InventorsYun Xu, Lei Zhang, Yang Song, Kewang Lu, David Luk
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Abstract
The present invention relates to oral composition and the method of preparation and use of such composition for inhibiting, reducing, and/or disrupting oral biofilm. The composition comprises a stabilizing matrix, a cationic biocide, and a peroxide source.
Claims20
A method for making an oral care product, comprising the steps of:
- a) dispersing and swelling polyvinylpyrrolidone in propylene glycol to obtain a first gel;
- b) dissolving a foaming agent in heated propylene glycol to obtain a first solution;
- c) adding a cationic biocide and optionally adding an orally acceptable compatible ingredient selected from the group consisting of anti-caries agent, sweetening agent, flavoring agent, coloring agent, chelating agent, and antioxidant to the first solution and thoroughly mixing to form a second solution;
- d) adding a first part of fumed silica to the second solution and homogenizing to obtain a second gel;
- e) mixing the first gel and the second gel to obtain a first paste;
- f) adding a second part of the fumed silica to the first paste and mixing to obtain a second paste;
- g) dispersing a micronized peroxide source powder evenly into the second paste to obtain an oral care product,
- h) where the oral care product consists of a peroxide source, a cationic biocide, a foaming agent, and a non-aqueous matrix, where the non-aqueous matrix consists of propylene glycol, fumed silica, polyvinylpyrrolidone, and any optional orally-acceptable compatible ingredient, where each optional ingredient is compatible with any other optional ingredient, the peroxide source, the cationic biocide, and the foaming agent, such that the non-aqueous matrix stabilizes the peroxide source and maintains the efficacy of the cationic biocide, and wherein the range of the weight ratio of propylene glycol, fumed silica and polyvinylpyrrolidone is:
- 1:0.03-0.15:0.01-0.08.
A method for making an oral care product that consists of a peroxide source, a cationic biocide, a foaming agent, and a non-aqueous matrix, said non-aqueous matrix consisting of propylene glycol, fumed silica, and polyvinylpyrrolidone, said non-aqueous matrix optionally further consisting of one or more orally-acceptable compatible ingredient selected from the group consisting of anti-caries agent, sweetening agent, flavoring agent, coloring agent, chelating agent, and antioxidant, where each optional ingredient is compatible with any other optional ingredient, the peroxide source, and the cationic biocide, such that the non-aqueous matrix stabilizes the peroxide source and maintains the efficacy of the cationic biocide, and wherein the range of the weight ratio of propylene glycol, fumed silica and polyvinylpyrrolidone is:
- 1:0.03-0.15:0.01-0.08, comprising the steps of:
- a) dispersing and swelling the polyvinylpyrrolidone in propylene glycol to obtain a first gel;
- b) dissolving a foaming agent in heated propylene glycol to obtain a first solution;
- c) adding the cationic biocide and any optionally included orally acceptable compatible ingredient to the first solution and thoroughly mixing to form a second solution;
- d) adding a first part of the fumed silica to the second solution and homogenizing to obtain a second gel;
- e) mixing the first gel and the second gel to obtain a first paste;
- f) adding a second part of the fumed silica to the first paste and mixing to obtain a second paste;
- g dispersing a micronized peroxide source powder evenly into the second paste to obtain an oral care product.
Dependencies are inferred from the claim text.