Use of nocardia rubra cell wall skeleton in regenerative medicine
AssigneeLiaoning Greatest Bio-Pharmaceutical Co., Ltd.
InventorsBo Gai, Chunyan Dou, Peisheng Jin, Yi Zhang, Guoying Zhang
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a use of Nocardia rubra cell wall skeleton in regenerative medicine, and in particular, to a use of Nocardia rubra (especially the cell wall skeleton thereof) in the following aspects: promoting proliferation, growth, differentiation and migration of stem cells, and improving the survival rate of the stem cells, wherein the stem cells are selected from: adult stem cells, iPSCs, and mesenchymal stem cells.
Claims9
A method of regulating stem cells comprising exposing the stem cells to a Nocardia rubra cell wall skeleton;
- wherein the ratio of the number of stem cells to the Nocardia rubra cell wall skeleton is 1 to 100 stem cells per 1 ng of the Nocardia rubra cell wall skeleton;
- wherein the stem cells are adipose-derived mesenchymal stem cells.
A method for promoting wound healing, comprising exposing a subject having a wound to a therapeutically effective amount of stem cells and a Nocardia rubra cell wall skeleton,
- wherein the stem cells are adipose-derived mesenchymal stem cells.
A pharmaceutical composition comprising:
- (i) stem cells, and
- (ii) Nocardia rubra cell wall skeleton, wherein the ratio of the number of stem cells to Nocardia rubra cell wall skeleton is:
- 1 to 100 stem cells to 1 ng of the Nocardia rubra cell wall skeleton;
- wherein the stem cells are adipose-derived mesenchymal stem cells.
Dependencies are inferred from the claim text.