Cryoprecipitate compositions and methods of preparation thereof
AssigneeCerus Corporation
InventorsLaurence Corash, Elan Weiner, Melody Holtan, Richard Benjamin
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Abstract
Provided herein are compositions and kits including a pathogen-inactivated cryoprecipitate suitable for infusion into a subject at least 1 day after thawing. The methods are useful in the efficient preparation of cryoprecipitates with desirable characteristics, including pathogen-inactivated cryoprecipitates that are suitable for infusion into a subject at least 1 day after thawing.
Claims61
A method of infusing a cryoprecipitate into a subject, comprising infusing into the subject a composition comprising a cryoprecipitate at least 1 day after thawing the composition comprising the cryoprecipitate, wherein the composition comprising the cryoprecipitate is pathogen-inactivated.
A method of infusing a cryoprecipitate into a subject, comprising infusing into the subject a cryoprecipitate produced by a method that comprises:
- a) preparing a cryoprecipitate from pathogen-inactivated plasma;
- b) freezing the cryoprecipitate;
- and
- c) thawing the frozen cryoprecipitate;
- wherein the cryoprecipitate is stored for at least 1 day at room temperature after thawing and prior to the infusion.
Dependencies are inferred from the claim text.