Rosa canina rosehip
AssigneeUniversita Degli Studi di Cagliari
InventorsAlessandra Piras, Antonella Ibba, Germano Orru′, Silvia Porcedda
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Abstract
A natural extract from seeds of Rosa canina which has a high antimicrobial activity is provided. The extract, which is diluted in water at different concentrations, constitutes an antimicrobial solution used in various fields: in environmental disinfection, both in humans and animals, as a base for antibacterial/antifungal preparations for topical, cutaneous or mucosal use. The extract is used in the preparation of disinfectant solutions that are used in the outpatient, hospital and domestic field, for air conditioner filters and for environments used for the preparation of food, as an ingredient in mouthwashes, toothpastes and skin creams.
Claims37
An aqueous extract obtained from seeds of Rosa canina by an extraction with a supercritical CO2, wherein the aqueous extract is obtained from a process comprising:
- (I) extracting dried and ground seeds of Rosa canina with CO2 in a supercritical phase as an extraction solvent under conditions of:
- a pressure ≤100 bar, a temperature ≤60° C., an extraction time ≤8 h, and a relative quantity of the extraction solvent (ms/m0) between 5 and 40, wherein ms/m0 is a total mass of the extraction solvent (ms) divided by a matrix mass subjected to an extraction (m0);
- (II) separating the extract obtained in (I) from the extraction solvent at a pressure ≤20 bar and a temperature ≤40° C.;
- (III) bringing the extract obtained in (II) to room temperature and pressure so that the extract spontaneously separates into two liquid phases:
- an oily phase and an aqueous phase;
- and
- (IV) recovering the aqueous phase in (III) in order to obtain the aqueous extract;
- wherein the aqueous extract has a dry fraction ranging between 0.1 and 10% mass/mass, and the aqueous extract comprises one or more organic compounds selected from:
- methyl-linoleate, methyl-oleate, methyl-palmitate, ethyl-linoleate, and ethyl-linolenate.
An extraction process of a plant matrix consisting of seeds of Rosa canina, comprising the following steps:
- (I) extracting dried and ground seeds of Rosa canina with CO2 in a supercritical phase as an extraction solvent under conditions of:
- a pressure ≤100 bar, a temperature ≤60° C., an extraction time ≤8 h, and a relative quantity of the extraction solvent (ms/m0) between 5 and 40, wherein ms/m0 is a total mass of the extraction solvent (ms) divided by a matrix mass subjected to an extraction (m0);
- (II) separating the extract obtained in (I) from the extraction solvent at a pressure ≤20 bar and a temperature ≤40° C.;
- (III) bringing the extract obtained in (III) to room temperature and pressure so that the extract spontaneously separates into two liquid phases:
- an oily phase and an aqueous phase;
- (IV) recovering the two liquid phases obtained in (III).
Dependencies are inferred from the claim text.