Cell structure, non-human model animal, method for producing non-human model animal, and method for evaluating test substance

A non-human model animal for a pancreatic cancer disease, comprising a transplant comprising:

• a cell structure which contains a plurality of biocompatible macromolecular blocks having amorphous shape and a size of 1 μm to 700 μm, a plurality of human-derived pancreatic cancer cells, and a plurality of human-derived mesenchymal cells,
• wherein the plurality of biocompatible macromolecular blocks are arranged in gaps between the plurality of cells,
• the plurality of biocompatible macromolecular blocks and the pluralities of cells are alternately arranged,
• a rich stromal tissue is formed around the plurality of human-derived pancreatic cancer cells,
• the biocompatible macromolecular blocks are obtained by pulverizing porous bodies comprising biocompatible macromolecules, and
• spaces are provided between the pancreatic cancer cells and the mesenchymal cells.