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US 12,508,309 B2Granted
Recombinant viral vector, immunogenic composition comprising same, and uses
AssigneeVacdiagn Biotechnology Co., Ltd
InventorsJianqing Xu, Yang Huang, Jiahao Sun
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Abstract
A recombinant viral vector, an immunogenic composition comprising the same, and uses. The recombinant viral vector comprises a polynucleotide encoding a cytokine, the cytokine being one or more selected from IL-7, IL-15, IL-21 or GM-CSF. The recombinant viral vector is useful in preparing an antitumor vaccine.
Claims9
A recombinant viral vector, comprising a polynucleotide encoding cytokines, wherein the cytokines are human IL-7, human IL-15, human IL-21 and human GM-CSF;
- wherein the encoding nucleic acid sequence of the human IL-15 is shown in SEQ ID NO:
- 1;
- the encoding nucleic acid sequence of the human GM-CSF is shown in SEQ ID NO:
- 3;
- the encoding nucleic acid sequence of the human IL-7 is shown in SEQ ID NO:
- 5;
- and the encoding nucleic acid sequence of the human IL-21 is shown in SEQ ID NO:
- 7.
5 more elements
Dependencies are inferred from the claim text.