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US 12,508,290 B2Granted
Use of Lactobacillus paracasei GMNL-346 for anti-oral cancer treatment and thereof
AssigneeGenmont Biotech Incorporation
InventorsWan-Hua Tsai, I-Ling Hsu, Wen-Wei Chang, Peng-Ju Chien, Yu-Chieh Hung
Life of this patent
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Abstract
A method for preventing or treating oral cancer includes administering a composition comprising Lactobacillus paracasei or a supernatant of the heat-killed Lactobacillus paracasei. A composition that contains an active ingredient with anti-oral cancer effect. The active ingredient is Lactobacillus paracasei GMNL-346 or the supernatant of the heat-killed GMNL-346. The deposition number of the Lactobacillus paracasei GMNL-346 is BCRC 910953 or CCTCC M 2019983.
Claims4
A method for treating human tongue squamous carcinoma cells (SAS, RRID:
- CVCL 1675), comprising administering a composition comprising a supernatant of heat-killed Lactobacillus paracasei GMNL-346, wherein the supernatant of heat-killed GMNL-346 derived from Lactobacillus paracasei GMNL-346 bacterial cultures are cultured for 48 hours and heat killed at 121° C. for 15 minutes and filtered through a 0.22 μm filter membrane and further filtered through a 3 KDa filter membrane;
- wherein the supernatant of heat-killed GMNL-346 contains molecular with a molecular weight less than 3 kDa;
- wherein a deposition number of the Lactobacillus paracasei GMNL-346 is CCTCC M 2019983.
Dependencies are inferred from the claim text.