Treatment of cerebral palsy using fibroblasts
AssigneeSpinalCyte, LLC
InventorsThomas Ichim, Pete O'Heeron
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Abstract
In some aspects, disclosed herein are methods and compositions for treatment or prevention of cerebral palsy using fibroblasts or derivatives thereof. Disclosed herein are fibroblasts and derivatives thereof capable of inducing neurogenesis and/or reducing inflammation in a subject. In some cases, the disclosed methods comprise use of conditioned fibroblasts. Fibroblasts may be conditioned with agents capable of enhancing therapeutic efficacy, for example oxytocin and/or human chorionic gonadotrophin (hCG).
Claims11
A method of treating cerebral palsy in a subject in need thereof, comprising providing to the subject a therapeutically effective amount of a composition comprising exosomes derived from fibroblasts.
Dependencies are inferred from the claim text.