Auto-powered synthetic skin
AssigneeCalifornia Institute of Technology
InventorsWei Gao, You Yu
Life of this patent
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Abstract
An auto-powered biosensor capable detecting a target molecule, and a method of powering the same, wherein the biosensor is fabricated with a microfluidics layer, a multimodal sensing layer comprising a biofuel cell and an electrode, and a logic circuit that may include a processor and non-transitory memory with computer executable instructions embedded thereon.
Claims17
A biosensor, comprising:
- a microfluidics layer comprising microchannels transversely oriented to obtain a biological sample, the biological sample comprising a target molecule and an energy molecule;
- a multimodal sensing layer comprising an electrode and a biofuel cell fluidically coupled to the microfluidics layer to receive the biological sample from the microchannels;
- and
- a logic circuit comprising a processor and a non-transitory memory with computer executable instructions embedded thereon;
- wherein the electrode is configured to detect a measurement of an electrical property corresponding to a target molecule present in the biological sample;
- wherein the biofuel cell comprises a lactate oxidase immobilized anode and a Pt-alloy cathode and configured to harvest energy from the target molecule to power the biosensor;
- wherein the lactate oxidase immobilized anode comprises hierarchical Ni microstructures (h-Ni).
A method for powering a biosensor comprised of a microfluidics layer comprising microchannels transversely oriented to obtain a biological sample, a multimodal sensing layer fluidically coupled to the microfluidics layer and comprising an electrode and a biofuel cell, and a logic circuit, the method comprising:
- receiving, a biological sample comprising an energy molecule, such that the biological sample can be channeled through the microfluidics layer to the multimodal sensing layer;
- and
- harvesting, with the biofuel cell, energy from an energy molecule present in the biological sample;
- wherein the biofuel cell comprises a lactate oxidase immobilized anode and a Pt-alloy cathode and is configured to harvest energy from the energy molecule present in the biological sample to power the biosensor;
- wherein the lactate oxidase immobilized anode comprises hierarchical Ni microstructures (h-Ni).
Dependencies are inferred from the claim text.