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US 12,507,941 B2Granted
Devices and methods for reducing anxiety and treating anxiety disorders
AssigneeSan Diego State University (SDSU) Foundation
InventorNader Amir
Life of this patent
Estimating the term…
Abstract
In alternative embodiments, provided are products of manufacture, including devices and integrated systems, and methods, for reducing error-related negativity (ERN) and anxiety, and for treating or ameliorating Anxiety Disorders such as Generalized Anxiety Disorder (GAD) or Social Anxiety Disorder (SAD) and obsessive-compulsive disorder (OCD).
Claims13
A product of manufacture, device or system for reducing error-related negativity (ERN), worry and/or anxiety, comprising a neurofeedback mechanism system,
- wherein the neurofeedback mechanism system is used on an individual in need thereof to reduce error-related negativity (ERN), worry and/or anxiety, and/or treating or ameliorating an anxiety disorder or obsessive-compulsive disorder (OCD), and/or treating or ameliorating the anxiety or worry in an individual in need thereof,
- wherein the neurofeedback mechanism system comprises:
- (a) an electro-encephalography (EEG) apparatus configured to be operatively linked to a computer and to the individual,
- wherein the EEG apparatus is configured to measure a physiologic response by the individual to stimuli transmitted by the computer, and the EEG apparatus transmits EEG data encompassing the physiologic response by the individual back to the computer,
- wherein the computer is configured to give the stimuli to the individual, and if the individual has a physiologic response to the stimuli the physiologic response is read by the EEG apparatus and physiologic response data is measured, and this physiologic response data is transmitted to the computer, which then provides feedback data based on physiologic response data of the individual,
- (b) a feedback mechanism operably connected with the computer, and the computer communicates with the individual after analysis of the individual's physiologic reaction to the stimuli,
- wherein the product of manufacture, device or system is configured to:
- filter the EEG data using an anti-aliasing low pass filter at about 130 Hz and digitized at about 500 Hz with about 24 bits of resolution;
- re-reference the EEG data to the average of signals obtained from TP9 and TP10 locations, and band-pass filter between about 0.1 and 30 Hz, comprising a non-causal Butterworth impulse response function, half-amplitude cut-off, and about 12 dB/oct roll-off;
- segment the EEG data for a trial beginning about 500 milliseconds (ms) prior to the physiologic response and continuing for about 1000 ms post physiologic response;
- or
- baseline correct data using a time period of between about −500 ms to −300 ms prior to the physiologic response.
9 more elements
A product of manufacture, device or system comprising:
- (a) an electro-encephalography (EEG) apparatus configured to be operatively linked to a computer and to an individual,
- wherein the EEG apparatus is configured to measure a physiologic response by the individual to a stimuli transmitted by the computer, and the EEG apparatus transmits EEG data encompassing the physiologic response by the individual back to the computer,
- wherein the computer is configured to give the stimuli to the individual, and if the individual has the physiologic response to the stimuli that physiologic response is read by the EEG apparatus and EEG data is generated measuring the physiologic response, and this data is transmitted to the computer, which then provides feedback based on the physiologic response of the individual,
- wherein the product of manufacture, device or system is configured to filter the EEG data using an anti-aliasing low pass filter at about 130 Hz and digitized at about 500 Hz with about 24 bits of resolution;
- wherein the product of manufacture, device or system is configured to re-reference the EEG data to the average of signals obtained from TP9 and TP10 locations, and band-pass filter between about 0.1 and 30 Hz, comprising a non-causal Butterworth impulse response function, half-amplitude cut-off, and about 12 dB/oct roll-off;
- wherein the product of manufacture, device or system is configured to segment the EEG data beginning about 500 milliseconds (ms) prior to the physiologic response from the individual and continuing for about 1000 ms after the physiologic response from the individual;
- and
- wherein the product of manufacture, device or system is configured to baseline correct data using a time period of between about −500 ms to −300 ms prior to the physiologic response.
5 more elements
Dependencies are inferred from the claim text.