Stabilizing matrices for implantable electrochemical biosensors

A device, comprising:

• a body;
• and
• an electrochemical biosensor,
• the electrochemical biosensor comprising a soft conductive composite composition,
• wherein the soft conductive composite composition includes:
• a silicone composition having an elastic modulus between 2 kPa and 9 kPa;
• a bioactive component;
• and
• carbon nanotubes in the silicone composition,
• wherein:
• the carbon nanotubes have at least 2 walls and the carbon nanotubes comprise a first plurality of carbon nanotubes modified by a first functional group and a second plurality of carbon nanotubes modified by the bioactive component;
• the first plurality of carbon nanotubes and the second plurality of carbon nanotubes are at a ratio of 1:2 to 1:20 w/w;
• the bioactive component is capable of performing a biochemical reaction with a substrate utilizing the second plurality of carbon nanotubes;
• the first functional group is selected from the group consisting of carboxylic acid, alkanes, alkenes, alkynes, amides, hydrides, heterocycles, transition metal oxides, peptides, DNAs, RNAs, and proteins;
• and
• the soft conductive composite composition coats at least a portion of the body.