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US 12,503,434 B2Granted
Nitrilotriacetic acid-containing lipidoid nanoparticles
AssigneeTrustees of Tufts College
InventorsQiaobing Xu, Yamin Li
Life of this patent
Estimating the term…
Abstract
Disclosed are noncationic lipidoid nanoparticles (LNPs) for His-tagged protein delivery.
Claims20
A compound of formula (I):
- or a pharmaceutically acceptable salt thereof, wherein
- Y is a divalent linker;
- W is —NR20—;
- RLipid is independently substituted or unsubstituted C1-20 alkyl, substituted or unsubstituted C2-20 alkenyl, substituted or unsubstituted C2-20 alknyl, substituted or unsubstituted C1-20 heteroalkyl, substituted or unsubstituted C2-20 heteroalkenyl, or substituted or unsubstituted C2-20 heteroalknyl;
- and
- R20 is RLipid.
3 more elements
A compound selected from the group consisting of:
Dependencies are inferred from the claim text.