Back to results
US 12,503,428 B2Granted
Tunable nitric oxide-releasing macromolecules having multiple nitric oxide donor structures
AssigneesThe University of North Carolina at Chapel Hill, Ligand Pharmaceuticals Incorporated
InventorsMark Schoenfisch, Yuan Lu, Nathan Stasko, Jian Bao
Life of this patent
Estimating the term…
Abstract
Provided here are nitric oxide-releasing compounds that include at least two different NO donor functional groups of the same class. In some embodiments, such nitric oxide-releasing compounds are macromolecules such as dendrimer and co-condensed silica. Pharmaceutical compositions, wound dressings, kits and methods of treatments are also provided herein.
Claims14
A nitric oxide-releasing macromolecule comprising
- at least two different NO donor structures of the same class,
- wherein the at least two different NO donor structures are each nitrosothiol donors.
Dependencies are inferred from the claim text.