Synthetic derivatives of oleoyl-lysophosphatidylinositol (oleoyl-LPI) and uses thereof

Abstract

The invention relates to oleoyl-lysophosphatidy linositol (oleoyl-LPI) and new synthetic derivatives thereof and uses thereof, and to pharmaceutical compositions comprising such compounds. The invention provides activators and/or up-regulators of glucoregulatory hormones such as glucagon like peptide-1 (GLP-1), and more specifically to agonists, partial agonists and reverse antagonists of GPR119 or activators of GLP-1 activity and/or synthesis and/or secretion, and pharmaceutical compositions comprising same, uses thereof in therapy of diabetes, obesity and other metabolic disorders.

Dependencies are inferred from the claim text.