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US 12,502,419 B2Granted
Chimeric proteins for selective lysis of bacteria
AssigneesBactoclear Holdings PTE. Ltd, Anisha Ambady
InventorsAnisha Ambady, Vivek Daniel Paul, R. Sanjeev Saravanan
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Abstract
The present invention provides chimeric ectolysins useful for selective suppression of certain targeted bacterial species while having little to no effect on closely related non-targeted bacterial species. Specifically, the disclosure provides polypeptides for selective suppression of growth of Staphylococcus aureus and/or S. hominis but not S. epidermidis. Compositions and methods for selective suppression of target bacterial species are also provided.
Claims17
A polypeptide comprising the amino acid sequence of SEQ ID NO:2, 4, 6, or 8.
Dependencies are inferred from the claim text.