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US 12,497,606 B2Granted
Mannanase variants and polynucleotides encoding same
AssigneeNovozymes A/S
InventorsVasudeva Prahlada Rao, Geetha Hiremath Mendez, Christian Isak Joergensen, Akshatha Venugopalan, Naveen Shivanand Raikar, Silja Poulose, Lars Olsen, Allan Svendsen, Jonatan Ulrik Fangel, Subith Krishna
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Abstract
The present invention relates to mannanase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and detergent compositions and methods of using the variants.
Claims19
A variant of a parent mannanase, wherein the variant comprises comprising a substitution at the position corresponding to position 168 of the amino acid sequence of SEQ ID NO:
- 1, wherein
- the substitution is with Ala, Arg, Asn, Asp, Cys, Glu, Gly, His, Ile, Leu, Lys, Met, Phe, Pro, Ser, Thr, Trp, Tyr or Val;
- the variant has mannanase activity;
- and
- the amino acid sequence of the variant has at least 85% sequence identity to the amino acid sequence of SEQ ID NO:
- 1 or SEQ ID NO:
- 2.
4 more elements
Dependencies are inferred from the claim text.