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US 12,497,550 B2Granted
Underwater adhesives formed by aggregation of free proteins into amyloid materials
AssigneeThe Government of the United States of America, as represented by the Secretary of the Navy
InventorsChristopher R. So, Michael C. Wilson
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Abstract
Adhesive formulations comprising bovine serum albumin, b-lactoglobulin, and/or a-lactalbumin can be applied and cured underwater to form a strong adhesive. Curing can be accomplished using heat or via a chemical denaturing component.
Claims3
A method of forming an adhesive bond underwater, the method comprising:
- providing a first component comprising between 25 and 100% w/v (weight/volume) bovine serum albumin, b-lactoglobulin, and/or a-lactalbumin in water;
- providing a second component comprising 6-10M of a protein denaturant, 0.8-1.2M of a sulfur-containing reducing agent, 5-15% w/v of charged surfactant, and 10-45% w/v hard filler material;
- mixing the first and second components in a volumetric ratio in the range of 0.5:2 to 2:0.5 and contacting them with a first surface underwater;
- and then
- contacting the mixed components with a second surface underwater thereby forming an adhesive bond between the surfaces.
2 more elements
Dependencies are inferred from the claim text.