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US 12,496,562 B2Granted
Sinuous microstructure mixing unit and use thereof
AssigneeShanghai Vitalgen Biopharma Co., Ltd.
InventorsXi Zhu, Chenxi Hou, Xiaoping Zhao
Life of this patent
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Abstract
The present invention relates to a sinuous microstructure mixing unit, and also relates to a microfluidic device having the unit, and the use of the unit or the device for preparing nanoparticles, such as lipid nanoparticles or self-assembled particles.
Claims14
A sinuous multi-layer (SML) microstructure mixing unit, comprising an inlet part, a confluence part, a multi-layer mixing part, and an outlet part in fluid communication, wherein
- each layer in the multi-layer mixing part is a sinuous flow path, and the sinuous flow path of each layer comprises n number of semi-circular rings or semi-elliptical rings, and any two adjacent semi-circular rings or semi-elliptical rings have opposite bending directions and are connected to each other via a straight flow path;
- projection shapes of two adjacent layers in the multi-layer mixing part always at least partially but not completely coincide throughout the flow path of the mixing part;
- and
- the inlet part comprises at least two inlets, and the inlets are in fluid communication with the confluence part, so that different fluids flowing in from the inlets converge at the confluence part.
1 more element
Dependencies are inferred from the claim text.