Composition for preventing, treating, or ameliorating viral infection disease, containing a complex of endoplasmic reticulum (ER) stress inhibitor and reactive oxygen species scavenger as active ingredients

Abstract

Disclosed is a composition for preventing, treating or ameliorating a viral infection disease, which is safe for human application since the safety of an ER stress inhibitor and a reactive oxygen species scavenger has already been verified. The disclosure utilizes inversely the mechanism of viruses which induces oxidative damage of a host cell and then activates viral replication and infection. Although not having direct specificity to a specific virus like existing vaccines, the composition can effectively inhibit proliferation of all viruses including oxidative stress, regardless of virus type or mutations. It can be applied as a sub-universal infection inhibitor and therapeutic agent as a limited alternative to vaccines that must be newly developed each year due to emergence of new viruses or viral mutations, and is expected to be used as a preventive agent or auxiliary agent to prevent epidemics.

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