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US 12,496,330 B2Granted
Methods of improving spinal fusion with abaloparatide
AssigneeRadius Health, Inc.
InventorsBeate Klara Maria Mannstadt, Bruce Mitlak
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Abstract
Provided herein are methods of enhancing spinal fusion and bone formation in subjects with spinal fractures, deformities or instability in the spine. The method includes administering (e.g., subcutaneously or transdermally) a therapeutically effective amount of abaloparatide to the subject.
Claims11
A method of treating a subject having a spinal fusion surgery, the method comprising administering a therapeutically effective amount of abaloparatide to the subject after having the spinal fusion surgery, wherein the administration is daily subcutaneous administration of 80 μg abaloparatide;
- wherein the treatment enhances spinal fusion, bone formation, or both, without elevating bone resorption;
- and wherein the enhanced spinal fusion or bone formation is determined by a CT scan.
Dependencies are inferred from the claim text.