Inflammatory diseases, comprising Lactobacillus sakei CVL-001 strain
AssigneeIndustry Foundation of Chonnam National University
InventorsJong Hwan Park, Dong Yeon Kim
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Abstract
The present invention relates to a composition for preventing or treating inflammatory diseases, comprising a Lactobacillus sakei CVL-001 strain. The composition activates NOD2, which is an inflammation regulator, and exhibits the effects of inhibiting weight loss and improving clinical activity scores (disease activity index; DAI) in an animal model in which ulcerative colitis is induced, and thus the present invention can be effectively used in the prevention, treatment or alleviation of inflammatory diseases.
Claims4
A method for alleviating or treating an inflammatory disease, the method comprising:
- administering to a subject in need thereof a composition comprising an effective amount of a Lactobacillus sakei CVL-001 strain deposited under accession number KCTC 13816BP,
- wherein the strain is an inactivated form obtained by killing with heat,
- wherein the composition comprises the strain at a concentration of 5×109 CFU/ml.
Dependencies are inferred from the claim text.