Back to results
US 12,492,294 B2Granted
Biocompatible porous materials and methods of manufacture and use
AssigneePoragen LLC
InventorsNicholas J. Manesis, Dylan B. Hollrigel
Life of this patent
Estimating the term…
Abstract
Methods and materials used for production of constructs having a porous open or semi-open celled structure. Constructs may include a porous matrix as a base and a biocompatible conformal coating thereon.
Claims16
A biocompatible open or semi-open celled material, comprising:
- an open or semi-open celled construct, including,
- a plurality of struts having a thickness from 30 microns to 95 microns, the plurality of struts including
- a polyurethane matrix;
- a silicone layer on the polyurethane matrix, the silicone layer having a thickness from 1 micron to 50 microns;
- and
- a hydrophilic layer on the silicone layer to impart wettability to the construct, the hydrophilic layer having a thickness less than 10 microns,
- wherein the polyurethane matrix is biostable, and
- the plurality of struts defining a plurality of pores, the construct being 60-98% open pore.
5 more elements
A biocompatible open or semi-open celled material, comprising:
- an open or semi-open celled construct, including,
- a plurality of struts the plurality of struts having a thickness from 30 microns to 90 microns, the plurality of struts including
- a polyurethane matrix;
- a silicone layer on the polyurethane matrix, the silicone layer having a thickness from 1 micron to 50 microns;
- and
- a hydrophilic layer on the silicone layer to impart wettability to the construct, the hydrophilic layer having a thickness less than 10 microns, wherein the polyurethane matrix is biostable, and
- the plurality of struts defining a plurality of pores, the construct being 60-98% open pore, wherein the construct, in an image of a top or a bottom of the construct, has an open area %, defined as open space between the plurality of struts, from 20-35%.
4 more elements
A biocompatible open or semi-open celled material, comprising:
- an open or semi-open celled construct, including,
- a plurality of struts having a thickness from 30 microns to 90 microns, the plurality of struts including
- a polyurethane matrix;
- a silicone layer on the polyurethane matrix, the silicone layer having a thickness from 1 micron to 50 microns;
- and
- a hydrophilic layer on the silicone layer to impart wettability to the construct, the hydrophilic layer having a thickness less than 10 microns, wherein the polyurethane matrix is biostable,
- the plurality of struts defining a plurality of pores, the construct being 60-98% open pore,
- wherein the construct, in an image of a top or a bottom of the construct, has an open area %, defined as open space between the plurality of struts, and
- wherein the polyurethane matrix in the absence of the silicone layer, in an image along a top or a bottom of the polyurethane matrix, has an open area %, defined as open space between the plurality of matrix struts, and
- wherein the difference between the construct open area % and the matrix open area % is less than 10%.
7 more elements
Dependencies are inferred from the claim text.