Back to results
US 12,491,516 B2Granted
Nanowell array device for high throughput sample analysis
AssigneeBattelle Memorial Institute
InventorsYing Zhu, Jongmin Woo, Ljiljana Pasa-Tolic
Life of this patent
Estimating the term…
Abstract
A device for biological sample preparation and analysis is disclosed. The device includes a substrate and a plurality of spaced apart arrays disposed on an upper surface of the substrate. Each array includes a plurality of reaction vessels, each reaction vessel having a hydrophilic surface. A hydrophilic ring surrounds each array. Methods of making and using the device are also disclosed.
Claims21
A device, comprising:
- a substrate having an upper surface;
- a plurality of spaced apart arrays disposed on the upper surface of the substrate, the arrays comprising a plurality of reaction vessels positioned on, or embedded within, the upper surface of the substrate, wherein the reaction vessels have a hydrophilic surface and a diameter from greater than 0 mm to 0.8 mm;
- and
- a hydrophilic ring surrounding each array, the hydrophilic ring positioned on, or embedded within, the upper surface of the substrate, wherein unoccupied regions of the upper surface of the substrate, including unoccupied regions located between reaction vessels within each array and unoccupied regions located between adjacent arrays, are hydrophobic.
1 more element
Dependencies are inferred from the claim text.