Buffer management system with manifold for bioprocessing system

A manifold for a buffer management system, the manifold comprising:

• a mixing junction;
• a buffer inlet line, the buffer inlet line in fluid communication with the mixing junction;
• a water for injection (WFI) inlet line, the WFI inlet line in fluid communication with the mixing junction;
• a discharge line, the discharge line in fluid communication with both the buffer inlet line and the WFI inlet line via the mixing junction;
• a first pump component, the first pump component disposed in the buffer inlet line, the first pump component configured to be operably arranged with a first pump motor to selectively generate a fluid displacement within the buffer inlet line;
• a second pump component, the second pump component disposed in the WFI inlet line, the second pump component configured to be operably arranged with a second pump motor to selectively generate a fluid displacement within the WFI inlet line;
• a buffer characteristic sensor, the buffer characteristic sensor disposed in the discharge line, the buffer characteristic sensor configured to detect a value of a buffer characteristic of a fluid in the discharge line and to generate a buffer characteristic signal indicative of the sensed value for the buffer characteristic;
• wherein the buffer inlet line includes a plurality of buffer inlet ports in fluid communication therewith, the WFI inlet line includes a water port in fluid communication therewith, and the discharge line includes a plurality of buffer discharge ports in fluid communication therewith, the plurality of buffer discharge ports corresponding to the plurality of buffer inlet ports.