# US 12,491,345 B2 · Temporary pacing guidewire

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- Number: US 12,491,345 B2
- Document ID: US12491345B2
- Status: Granted
- Kind: B2
- Application number: 18/236,014
- Filed: 2023-08-21
- Published: 2024-02-22
- Granted: 2025-12-09
- Earliest claimed: 2022-08-19
- Assignees: Greatbatch Ltd.
- Applicants: Greatbatch Ltd.
- Inventors: Ling Wang; David Thomsen; Jeremy Hansen
- Web page: https://patentgrep.com/patent/US12491345B2

## CPC

- A61M 25/09: Guide wires
- A61N 1/056: {Transvascular endocardial electrode systems}
- A61N 1/0595: {Temporary leads}
- A61M 25/0045: {multi-layered, e.g. coated (coating materials A61L29/08)}
- A61M 2025/0046: {Coatings for improving slidability}
- A61M 2025/09083: {having a coil around a core}
- A61M 2025/09183: {having tools at the distal tip}
- A61M 2205/054: with electrotherapy
- A61M: DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY (introducing media into or onto the bodies of animals A61D7/00; means for inserting tampons A61F13/26; devices for administering food or medicines orally A61J; containers for collecting, storing or administering blood or medical fluids A61J1/05); DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY (surgery A61B; chemical aspects of surgical articles A61L); DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR {(Electrotherapy, e.g. producing anaesthesia by the use of alternating or intermittent currents A61N1/36021)}
- A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B)

## Abstract

In various examples, a guidewire for temporary pacing of tissue includes an elongate core wire and a coil disposed along at least a portion of a length of the core wire. The coil is disposed radially outwardly from and around the core wire, wherein a core axis and a coil axis are substantially aligned. At least one electrode is disposed along the guidewire and includes an uninsulated portion of the core wire disposed within an electrode section of the coil. A spacing between adjacent windings of the electrode section of the coil is configured to allow a stimulation pulse to travel from the uninsulated portion of the core wire, through the spacing between the adjacent windings of the electrode section, and to the tissue in order to stimulate the tissue.

## Claims

### Claim 1

A guidewire for temporary pacing of tissue, the guidewire including a guidewire proximal end, a guidewire distal end, and a guidewire length extending from the guidewire proximal end to the guidewire distal end, the guidewire comprising:
an elongate core wire, the core wire including a core proximal end, a core distal end, and a core length extending from the core proximal end to the core distal end, the core wire including a core axis along the length of the core wire;
a coil disposed along at least a portion of the length of the core wire, the coil including a coil length and a coil axis along the length of the coil, the coil including a first pitch along at least some of the length of the coil, the coil being disposed radially outwardly from and around the core wire, wherein the core axis and the coil axis are substantially aligned; and
at least one electrode disposed along the guidewire, the at least one electrode including an uninsulated portion of the core wire disposed within an electrode section of the coil, the electrode section of the coil including a second pitch, wherein the second pitch is greater than the first pitch, such that a spacing between adjacent windings of the electrode section of the coil is configured to allow a stimulation pulse to travel from the uninsulated portion of the core wire, through the spacing between the adjacent windings of the electrode section, and to the tissue in order to stimulate the tissue.

### Claim 2 (depends on 1)

The guidewire of claim 1, wherein the core wire includes insulation along at least a portion of the core wire other than the uninsulated portion.

### Claim 3 (depends on 2)

The guidewire of claim 2, wherein the core wire is insulated along the length of the core wire except at the uninsulated portion of the core wire disposed at a location of the at least one electrode.

### Claim 4 (depends on 1)

The guidewire of claim 1, wherein the coil of the electrode section having the second pitch includes a distance between adjacent windings of the coil that is greater than a distance between adjacent windings of the coil having the first pitch.

### Claim 5 (depends on 1)

The guidewire of claim 1, wherein the guidewire includes a J-shaped portion proximate the guidewire distal end.

### Claim 6 (depends on 5)

The guidewire of claim 5, wherein the at least one electrode is located on the J-shaped portion.

### Claim 7 (depends on 1)

The guidewire of claim 1, wherein the at least one electrode includes two or more electrodes.

### Claim 8 (depends on 1)

The guidewire of claim 1, wherein the coil includes a coating around at least part of the coil.

### Claim 9 (depends on 1)

The guidewire of claim 1, wherein the at least one electrode includes at least one weld between the uninsulated portion of the core wire and the electrode section of the coil to create a lower-resistance path to stimulate the tissue.

### Claim 10 (depends on 1)

The guidewire of claim 1, wherein the guidewire proximal end includes a connector configured to electrically couple an external stimulation device to the core wire, the external stimulation device being configured to provide the stimulation pulse to be delivered by the at least one electrode in order to stimulate the tissue.

### Claim 11 (depends on 10)

The guidewire of claim 10, wherein the connector includes the core proximal end extending from within the guidewire, at least a portion of the core proximal end being uninsulated.

### Claim 12 (depends on 11)

The guidewire of claim 11, wherein the connector includes an insulation ring electrically insulating the coil from the core proximal end.

### Claim 13

A guidewire for temporary pacing of tissue, the guidewire including a guidewire proximal end, a guidewire distal end, and a guidewire length extending from the guidewire proximal end to the guidewire distal end, the guidewire comprising:
an elongate core wire, the core wire including a core proximal end, a core distal end, and a core length extending from the core proximal end to the core distal end, the core wire including a core axis along the length of the core wire;
a coil disposed along at least a portion of the length of the core wire, the coil including a coil length and a coil axis along the length of the coil, the coil including a first pitch along at least some of the length of the coil, the coil being disposed radially outwardly from and around the core wire, wherein the core axis and the coil axis are substantially aligned; and
at least one electrode disposed along the guidewire, the at least one electrode including an uninsulated portion of the core wire disposed within an electrode section of the coil, the electrode section of the coil including a second pitch greater than the first pitch, wherein the coil of the electrode section having the second pitch includes a distance between adjacent windings of the coil that is greater than a distance between adjacent windings of the coil having the first pitch, such that a spacing between adjacent windings of the electrode section of the coil is configured to allow a stimulation pulse to travel from the uninsulated portion of the core wire, through the spacing between the adjacent windings of the electrode section, and to the tissue in order to stimulate the tissue.

### Claim 14 (depends on 13)

The guidewire of claim 13, wherein the core wire includes insulation along at least a portion of the core wire, the core wire at least being uninsulated at the uninsulated portion of the core wire disposed at a location of the at least one electrode.

### Claim 15 (depends on 13)

The guidewire of claim 13, wherein the at least one electrode includes two or more electrodes.

### Claim 16 (depends on 13)

The guidewire of claim 13, wherein the at least one electrode includes at least one weld between the uninsulated portion of the core wire and the electrode section of the coil to create a lower-resistance path to stimulate the tissue.

### Claim 17 (depends on 13)

The guidewire of claim 13, wherein the guidewire proximal end includes a connector configured to electrically couple an external stimulation device to the core wire, the external stimulation device being configured to provide the stimulation pulse to be delivered by the at least one electrode in order to stimulate the tissue.

### Claim 18 (depends on 17)

The guidewire of claim 17, wherein the connector includes:
the core proximal end extending from within the guidewire, at least a portion of the core proximal end being uninsulated; and
an insulation ring electrically insulating the coil from the core proximal end.

### Claim 19

A guidewire for temporary pacing of tissue, the guidewire including a guidewire proximal end, a guidewire distal end, and a guidewire length extending from the guidewire proximal end to the guidewire distal end, the guidewire comprising:
an elongate core wire, the core wire including a core proximal end, a core distal end, and a core length extending from the core proximal end to the core distal end, the core wire including a core axis along the length of the core wire, wherein the core wire includes insulation along at least a portion of the core wire;
a coil disposed along at least a portion of the length of the core wire, the coil including a coil length and a coil axis along the length of the coil, the coil including a first pitch along at least some of the length of the coil, the coil being disposed radially outwardly from and around the core wire, wherein the core axis and the coil axis are substantially aligned; and
two or more electrodes disposed along the guidewire, each of the electrodes including an uninsulated portion of the core wire disposed within an electrode section of the coil, the electrode section of the coil including a second pitch greater than the first pitch, the coil of the electrode section having the second pitch including a distance between adjacent windings of the coil that is greater than a distance between adjacent windings of the coil having the first pitch, such that a spacing between adjacent windings of the electrode section of the coil is configured to allow a stimulation pulse to travel from the uninsulated portion of the core wire, through the spacing between the adjacent windings of the electrode section, and to the tissue in order to stimulate the tissue.

### Claim 20 (depends on 19)

The guidewire of claim 19, wherein each of the two or more electrodes includes at least one weld between the uninsulated portion of the core wire and the electrode section of the coil to create a lower-resistance path to stimulate the tissue.
