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US 12,491,269 B2Granted
Radioactive yttrium phosphate suspension and method of preparing the same
AssigneeVivos, Inc.
InventorsMichael Korenko, David Swanberg
Life of this patent
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Abstract
A radioactive yttrium phosphate suspension, including a phosphate buffered saline solution and a plurality of radioactive yttrium phosphate particles suspended in the phosphate buffered saline solution. The plurality of radioactive yttrium phosphate particles are between 0.1 um to 2 um in diameter. The plurality of radioactive yttrium phosphate particles are generally spherical. The YPO4 particle concentration is in the range of 40 mg/ml to 125 mg/ml.
Claims18
A radioactive yttrium phosphate suspension, comprising:
- a phosphate buffered saline solution;
- and
- a plurality of radioactive yttrium phosphate particles suspended in the phosphate buffered saline solution;
- wherein the plurality of radioactive yttrium phosphate particles are between 0.03 um and 10 um in diameter;
- wherein the plurality of radioactive yttrium phosphate particles are generally spherical;
- and
- wherein the YPO4 particle concentration is in the range of 40 mg/ml to 125 mg/ml.
4 more elements
A radioactive phosphate suspension, comprising:
- a phosphate buffered saline solution;
- and
- a plurality of radioactive metal phosphate particles suspended in the phosphate buffered saline solution, wherein each metal phosphate particle includes a metal cation and a phosphate functional group;
- and
- wherein the plurality of radioactive metal phosphate particles are between 0.03 um and 10 um in diameter.
2 more elements
A radioactive metal phosphate suspension, comprising:
- a phosphate buffered saline solution;
- and
- a plurality of radioactive metal phosphate particles suspended in the phosphate buffered saline solution, wherein each metal phosphate particle includes a metal cation and a phosphate functional group;
- wherein the plurality of radioactive metal phosphate particles are between 0.03 um and 10 um in diameter;
- wherein the metal phosphate particles are selected from the group consisting of lanthanide phosphates, actinide phosphates, alkali earth phosphates, transition metal phosphates, and combinations thereof;
- wherein the metal phosphate particles have solubility of less than 1×10-6 mole/liter;
- wherein the phosphate functional group includes phosphorus isotopes selected from the group consisting of 31P, 32P, 33P, and combinations thereof;
- and
- wherein the metal phosphate particles provide a dosage of between 100 uCi and 300 mCi.
6 more elements
Dependencies are inferred from the claim text.