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AssigneeThe Regents of the University of California
InventorsElaine Y. Hsiao, Helen E. Vuong
Estimating the term…
Disclosed herein are methods for promoting healthy neural development in an unborn baby, which include administering to a maternal subject gestating the unborn baby a composition or a bacterial composition. Compositions can include trimethylamine N-oxide (TMAO), 5-aminovalerate (5-AV), imidazole propionate (IP), hippurate (HIP), or a combination thereof, and the bacterial compositions can include bacteria of the order Clostridiales. Also disclosed are methods for conditioning a female subject for bringing about offspring with healthy neural development. Additionally disclosed are methods for reducing adverse effects of antibiotic treatment on an unborn baby in a pregnant subject. Also disclosed are methods for selecting a female subject for conditioning to foster healthy neural development in offspring.
A method of promoting healthy neural development in an unborn baby, the method comprising administering to a maternal subject gestating the unborn baby a composition comprising trimethylamine N-oxide (TMAO), 5-aminovalerate (5-AV), imidazole propionate (IP), and hippurate (HIP).
A method of conditioning a female subject for fostering healthy neural development in offspring, the method comprising
A method of reducing adverse effects of antibiotic treatment on an unborn baby in a pregnant subject, the method comprising administering to the pregnant subject, conjointly with the antibiotic treatment, a composition comprising trimethylamine N-oxide (TMAO), 5-aminovalerate (5-AV), imidazole propionate (IP), and hippurate (HIP).
Dependencies are inferred from the claim text.