Method for producing oral disintegrating film comprising poorly soluble drug

A method for producing an oral disintegrating film comprising a poorly soluble drug, the method comprising the following steps:

• a) producing a mixture by melting a film-forming polymer, a solubilizer, a plasticizer, and a poorly soluble drug;
• and
• b) printing the melted mixture by a 3D printing technique, wherein the film-forming polymer is polyethylene oxide, wherein the solubilizer is a vinylpyrrolidone-vinyl acetate copolymer, wherein the plasticizer is poloxamer 407 or poloxamer 188, wherein the poorly soluble drug is one or more Biopharmaceutic Classification System Class II drugs selected from the group consisting of olanzapine, haloperidol, glibenclamide, and indapamide, and wherein printing is performed by spraying at a pneumatic pressure of 450 kPa to 500 kPa.