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US 12,486,500 B2Granted
Method for stimulating the gene expression in endometrial cells
AssigneeTelea Medical Group S.R.L.
InventorsGianantonio Pozzato, Alessandro Pozzato
Life of this patent
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Abstract
An in-vitro method for stimulating the gene expression of at least one of XOXA10, LIF, ITGB3, XOXA11 and ITGAV genes in endometrial cells comprising applying on such endometrial cells electric current waves having a sinusoidal waveform with a fundamental frequency higher than 2 MHz, preferably of about 4 MHz, for a predefined amount of time.
Claims5
An in vitro process for increasing expression of a gene in endometrial cells, comprising the steps of:
- contacting a culture of endometrial cells with electrodes and applying electric current waves having a sinusoidal waveform having a fundamental frequency higher than 2 MHz to about 4 MHz for a predetermined amount of time;
- and
- assaying the contacted cells for the expression of a gene, wherein the gene is selected from the group consisting of HOXA10, LIF, ITGB3, HOXA11, and ITGAV, and wherein expression of the gene is increased in response to the electric current waves applied to the endometrial cells.
Dependencies are inferred from the claim text.