Fungal (1,3)-beta-d glucan-directed monoclonal antibody, coding genes thereof, expression thereof and application thereof

Abstract

The present application provides a fungal (1,3)-Beta-D glucan-directed monoclonal antibody, coding genes thereof, expression thereof and application thereof and belongs to the technical area of medicine & biomedical detection. The antibody contains complementarity determining regions of a light chain variable region and its amino acid sequences contain: VL-CDR1 shown by SEQ ID NO:1, VL-CDR2 shown by SEQ ID NO:2 and VL-CDR3 shown by SEQ ID NO:3; the antibody also contains cornplementarity determining regions of a heavy chain variable region and its amino acid sequences contain: VH-CDR1 shown by SEQ ID NO:4, VH-CDR2 shown by SEQ ID NO:5 and VH-CDR3 shown by SEQ ID NO:6. This antibody specifically binds with the fungal (1,3)-Beta-D glucan, has strong antibody affinity and does not trigger cross reaction with interference substances.

Dependencies are inferred from the claim text.