Receptor tyrosine kinase inhibitors for treatment of protein kinase modulation-responsive disease or disorder
AssigneeThe United States of America, as represented by the Secretary, Department of Health and Human Services
InventorsGiovanna Tosato, Michael J. DiPrima, Harald Schwalbe, Alix Tröster, Denis Kudlinzki, Nathalie Jores
Life of this patent
Estimating the term…
Abstract
Ephrin type receptor tyrosine kinase inhibitors, also known as Eph tyrosine kinase receptor inhibitors, for treating cancer, an inflammatory disease, an autoimmune disease, or a degenerative disease characterized at least in part by the abnormal activity or expression of the Eph receptor tyrosine kinase. The inhibitors are particularly useful for treating certain cancers.
Claims5
A method of treating colorectal cancer in a subject, comprising administering to the subject a therapeutically effective amount of a compound selected from
- or a pharmaceutical composition thereof, wherein the colorectal cancer is characterized by the abnormal activity or expression of the Eph receptor tyrosine kinase.
A method of treating colorectal cancer in a subject, comprising administering to the subject a therapeutically effective amount of a compound selected from
- or a pharmaceutical composition comprising the compound, thereby treating the colorectal cancer.
Dependencies are inferred from the claim text.